Sinopsis: Tim Allen interpreta a un padre de familia que mientras investiga en su trabajo un incidente en un laboratorio de animales se infecta de una sustancia que lo convierte en perro.
Equipo creativo principal:
Reparto:
Tim AllenDave Douglas 
Kristin DavisRebecca Douglas 
Zena GreyCarly Douglas 
Spencer BreslinJosh Douglas 
Danny GloverKen Hollister 
Robert Downey Jr.Dr. Kozak 
Joshua LeonardJustin Forrester 
Shawn PyfromTrey 
Bess WohlDr. Gwen Lichtman 
Jarrad PaulLarry 
Annabelle GurwitchJustin Forrester's Attorney 
Jane CurtinJudge Claire Whittaker 
Philip Baker HallLance Strictland 
Joel David MoorePound Employee 
Jeanette BroxJaney 
Kevin CooneyDoctor 
Rhea SeehornLori 
Craig KilbornBaxter 
Koji KataokaMonk 
Casey SanderLeader Courtney McLeanBailiff 
Laura KightlingerMs. Foster - Teacher 
Phaedra NielsonCo-Worker 
Eric WinzenriedAnimal Control Officer 
John GatinsHomeless Guy Jordyn ColemonTracy (as Jordyn Michelle Colemon) 
Jan DevereauxWoman in Restaurant 
Jane HajdukNews Reporter Rocky La PortePolice Officer 
Mic RodgersBus Driver 
Leonard L. ThomasMercenary Mark Robert EllisFootball Coach 
Adam HicksQuarterback Michael Tyler HenryObnoxious Player #1 Darby C. WilsonObnoxious Player #2 Rick ShusterMerc. Pilot Christina BergstromStenographer Luke GregoryAnimal Control Officer #2 David 'Goldy' GoldsmithMan in Elevator Janine EdwardsKozak Secretary 
Brandon Ray OliveGrant - Strictland Office Worker Chris WeaverProtest Leader 
Philip PavelHighway Driver (as Phil Pavel) 
Crystal the MonkeyCapuchin (uncredited) Linda GriffinAdditional Voice (voice) (uncredited) 
Jesse HeimanPound Employee (uncredited) Créditos técnicos adicionales:
Anita HartUtility Stunts · Crew 
Bill WalshOriginal Film Writer · Writing Chuck DukeAnimation · Visual Effects 
Daniel T. DorranceArt Direction · Art 
David HobermanProducer · Production Don TaitOriginal Film Writer · Writing 
Felix SaltenNovel · Writing Howard R. CampbellLighting Artist · Lighting Jeanne McCarthyCasting · Production Juel BestropCasting · Production Karin SilvestriUtility Stunts · Crew 
Kenny EndosoUtility Stunts · Crew Leslie McDonaldProduction Design · Art Lillie HaywardOriginal Film Writer · Writing Matthew CarrollExecutive Producer · Production 
Michael RunyardUtility Stunts · Crew Molly MaginnisCostume Design · Costume & Make-Up Ned BastilleEditor · Editing R. Adam ChambersChief Lighting Technician · Lighting 
Robert SimondsExecutive Producer · Production Ronald R. ReissSet Decoration · Art Tim AllenProducer · Production 
Tim TrellaStunt Coordinator · Crew 
Todd LiebermanExecutive Producer · Production William FayExecutive Producer · Production Pósters:
Imágenes:
Logos:
Tráilers:
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