Sinopsis: Hace millones de años, en los albores del nacimiento del homo sapiens, unos simios descubren un monolito que les lleva a un estadio de inteligencia superior. Otro monolito vuelve a aparecer, millones de años después, enterrado en una luna, lo que provoca el interés de los científicos humanos. Por último, HAL 9000, una máquina de inteligencia artificial, es la encargada de todos los sistemas de una nave espacial tripulada durante una misión de la NASA.
Equipo creativo principal:
Reparto:
Keir DulleaDr. David Bowman 
Gary LockwoodDr. Frank Poole 
William SylvesterDr. Heywood Floyd 
Douglas RainHAL 9000 (voice) 
Daniel RichterMoonwatcher 
Leonard RossiterDr. Andrei Smyslov 
Margaret TyzackElena 
Robert BeattyDr. Ralph Halvorsen Sean SullivanDr. Roy Michaels Frank W. MillerMission Controller (voice) Bill WestonAstronaut 
Ed BishopAries-1B Lunar Shuttle Captain 
Glenn BeckAstronaut 
Alan GiffordPoole's Father 
Ann GillisPoole's Mother 
Edwina CarrollAries-1B Stewardess 
Penny BrahmsStewardess Heather DownhamStewardess Mike LovellAstronaut John AshleyApe Jimmy BellApe 
David CharkhamApe Keith DennyApe Jonathan DawApe Péter DelmárApe Terry DugganApe Attacked by Leopard David FleetwoodApe Danny GroverApe Brian HawleyApe David HinesApe Anthony JacksonApe John JordanApe Scott MacKeeApe Laurence MarchantApe Darryl PaesApe Joe RefaloApe Andy WallaceApe Bob WilymanApe Richard WoodsApe Killed by Moon-Watcher 
Maggie LondonHostess in Elevator (uncredited) 
Chela MatthisonReceptionist (uncredited) Judy KeirnVoice Print Identification Girl (uncredited) 
Vivian KubrickFloyd's Daughter (uncredited) 
Kenneth KendallBBC-12 Announcer (uncredited) 
Kevin ScottMiller (uncredited) Martin AmorInterviewer (uncredited) S. Newton AndersonYoung Man (uncredited) Sheraton Blount(uncredited) Ann Bormann(uncredited) Julie Croft(uncredited) Penny Francis(uncredited) Marcella Markham(uncredited) Irena MarrRussian Scientist (uncredited) Krystyna MarrRussian Scientist (uncredited) Kim Neil(uncredited) Jane Pearl(uncredited) Penny Pearl(uncredited) 
Burnell TuckerTMA-1 Site Photographer (uncredited) 
John SwindellsTMA-1 Site Technician #1 (uncredited) John CliffordTMA-1 Site Technician #2 (uncredited) 
Stanley KubrickAstronaut Breathing (voice) (uncredited) Harry FielderMoonwalker (uncredited) Créditos técnicos adicionales:
Anthony MastersProduction Design · Art Bobby ClarkStunts · Crew 
Brian JohnsonSpecial Effects · Crew Con PedersonVisual Effects Supervisor · Visual Effects David de WildeEditorial Staff · Crew David Wynn-JonesClapper Loader · Camera 
Derek CracknellFirst Assistant Director · Directing Dick FriftConstruction Coordinator · Art 
Douglas TrumbullVisual Effects Supervisor · Visual Effects Douglas TrumbullVisual Effects Ernest ArcherProduction Design · Art Frederick I. Ordway IIIScientific Consultant · Crew George WattsAssistant Camera · Camera Graham FreebornMakeup Artist · Costume & Make-Up H.L. BirdSound mixer · Sound Hardy AmiesWardrobe Designer · Costume & Make-Up Harry LangeProduction Design · Art James LiggatCasting · Production 
John AlcottAdditional Photography · Camera John FrancisStunt Coordinator · Crew John HoesliArt Direction · Art Kelvin PikeCamera Operator · Camera Les BowieSpecial Effects · Crew Malcolm StewartSound Designer · Sound Mary GibsonWardrobe Supervisor · Costume & Make-Up Ray LovejoyEditor · Editing Robert CartwrightSet Decoration · Art Stanley KubrickProducer · Production Stanley KubrickVisual Effects Stuart FreebornMakeup Artist · Costume & Make-Up Tom HowardVisual Effects Supervisor · Visual Effects Victor LyndonProducer · Production Wally VeeversVisual Effects Supervisor · Visual Effects Winston RyderSound Editor · Sound Pósters:
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Logos:
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Escenas:
Detrás de las cámaras:
Extras:
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